Acute Chagas Disease: New Global Challenges for an Old Neglected Disease
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منابع مشابه
Acute Chagas Disease: New Global Challenges for an Old Neglected Disease
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information concerning the chronic phase of human Chagas disease, particularly the severe cardiac form, is available in the literature. However, information conce...
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Chagas disease which is caused by the haemoflagellate Trypanosoma cruzi is classically transmitted by Reduviid bugs of the genera Triatoma and Rhodnius and occurs when the bugs bite humans and pass infective trypomastigotes in their stools which enter the blood through puncture wound in the skin (1). Chagas disease has been recognized as a neglected tropical disease with between eight and nine ...
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Chagas disease continues to be a significant public health problem, as ca. 10 million people are still infected with T. cruzi in Latin America. Decades after primary infection, 30% of individuals can develop a form of chronic inflammatory cardiomyopathy known as Chagas disease cardiomyopathy (CCC). Data from both murine models and human studies support the view that an autoimmune response as we...
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1Department of Infectious Diseases, Singapore General Hospital 2Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School Address for Correspondence: Dr Jenny Low, Department of Infectious Diseases, Singapore General Hospital, Outram Road, Singapore 169608. Email: [email protected] Singapore has experienced yet another epidemic. With more than 13,000 cases reported as of mid ...
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Biomarkers or biosignature profiles have become accessible over time in population-based studies for Chagas disease. Thus, the identification of consistent and reliable indicators of the diagnosis and prognosis of patients with heart failure might facilitate the prioritization of therapeutic management to those with the highest chance of contracting this disease. The purpose of this paper is to...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2014
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0003010